CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
Tumor markers in familial Mediterranean fever and their correlation with the frequency of attacks
Authors
Balaban Y.H.
Sarer-Yurekli B.P.
+4 more
Shorbagi A.
Simsek H.
Tatar G.
Yilmaz R.
Publication date
1 January 2008
Publisher
Abstract
PubMed ID: 19026128Objective. Serum levels of tumor markers can be elevated in several benign diseases affecting the serosal surfaces. Familial Mediterranean fever (FMF) is a genetic disease characterized by acute attacks of fever and inflammation of the serosal membranes. The aim of this study was to examine the levels of tumor markers in FMF patients and their correlation with the frequency of attacks. Methods. Serum levels of CA 125, CA 19-9, CA 15-3, CA 72-4, CEA, and AFP were measured by ELISA in 36 patients with a definitive diagnosis of FMF (21 males, l5 females, mean age 36.4±10.3 yrs) and in 19 healthy controls. Results. Serum levels of all tumor markers were normal in the controls. In FMF patients serum levels of CA 125, CA 19.9, CA 15.3, CEA and AFP were within normal ranges, whereas CA 72.4 was significantly higher than in the controls (p=0.001). Ha~f of the FMF patients showed increased levels of CA 72.4; the mean level was lower in those in complete remission. However, no statistically significant correlation was found between FMF attacks and acute phase reactant levels. Conclusion. With the exception of Ca 72.4, serum levels of tumor markers are not affected by changes in inflammatory cytokines levels during FMF attacks. © Copyright Clinical and Experimental Rheumatology 2008
Similar works
Full text
Available Versions
Ege University Institutional Repository
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:gcris.ege.edu.tr:11454/209...
Last time updated on 23/11/2023