Changes in peripheral blood levels of platelet-activating factor after orthotopic liver transplantation

Abstract

Platelet-Activating factor (PAF) is a phospholipid mediator structurally characterized as 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine with a broad range of biological activities. PAF has been implicated as a mediator of the acute allergic and inflammatory response as well as in the pathogenesis of hyperacute rejection in organ transplantation, which is mediated..