synthesis of copper ion incorporated uricase-based hybrid nanoflowers and their enhanced cataltic properties

Abstract

Enzymehas been unique properties due to eco-friendly nature and superior catalyticactivity, high reaction specificity and low toxicity [1]. However, theirefficient use is limited due to some connatural disadvantages due to beingwithout stability, difficulty in recovery and reusability, loss of catalyticactivity after administration into the reaction and high cost. In order toovercome these disadvantages, several immobilization approaches have beendeveloped. The expectancy with enzyme immobilization is to improve bothcatalytic activity and stability [2]. Recently, hybrid materials, combiningwith the advantages of organic and inorganic components have been widelyapplied for enzyme immobilization because of their unique properties. Herein,we present a study on the formation, catalytic activity and stability of hybridnanoflowers (hNFs) containing uricase and copper ions.</p