Not AvailableHexane, ethyl acetate and methanol extractives of Coleus forskohlii roots exhibit mycelial growth inhibition of Colletotrichum gloeosporioides and spore germination inhibition of Alternaria solani. Forskolin, a diterpene present in C. forskohlii exhibit dose dependent spore germination inhibition of A. solani, this being the first report on the antifungal activity of this compound. Estimation of forskolin in the extractives by HPLC showed that while hexane extractive contained 3.9% forskolin and ethyl acetate extractive contained 4.6% forskolin, while the methanol extractive did not contain forskolin. The results clearly show that forskolin is one of the antifungal compounds present in the plant.Not Availabl
