Though it was introduced as the magical therapy of preeclampsia, aspirin was soon a great disappointment for many obstetricians. The conflicting results in the literature may be due to the differences in socioeconomic and genetic factors of the study groups, definition criteria of preeclampsia and its complications and maybe the most important of all, the prejudice of the authors in designing the study and interpretation of the results. In this literature review, the main population-based studies in the literature were compared in means of methodology and results. It is obvious that aspirin is neither a miracle nor a placebo, but is a promising drug to be used with certain limitations
