Anil Sazak

Guan

Hai Deng

Jioji Tabudravu

Jukes

Kojo Acquah

Kwaku Kyeremeh

Marcel Jaspars

Parsek

Saitou

Wael Houssen

Marine Drugs

English

PubMed

Kyeremeh, Kwaku

Acquah, Kojo

Sazak, Anil

Houssen, Wael E

Tabudravu, Jioji

Deng, Hai

Jaspars, Marcel

The Open University

3-Hydroxylation of the polycyclic tetramate macrolactam in the biosynthesis of antifungal HSAF from lysobacter enzymogenes C3.

a new antimicrobial alkaloid from marine Micromonospora

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a new potent antileukemic simaroubolide from Brucea antidysenterica.

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Actinomycetes for marine drug discovery isolated from mangrove soils and plants

Acyl homoserine-lactone quorum-sensing signal generation.

an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis.

Chandrananimycins A–C: Production of novel anticancer antibiotics from a marine Actinomadura sp. isolate M048 by variation of medium composition and growth conditions.

Chinikomycins A and B: Isolation, structure elucidation, and biological activity of novel antibiotics from a marine Streptomyces sp. isolate M045.

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria.

Confidence limits on phylogeny: An approach using the bootstrap. Evolution

Evolution of Protein Molecules.

inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18–032.

Introducing EzTaxon-e: A prokaryotic 16S rRNA gene sequence database with phylotypes that represent uncultured species.

MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.

Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa. Biochemistry

N-acylhomoserine lactone-mediated quorum sensing: A twist in the tail and a blow for host immunity.

Novel caprolactones from a marine streptomycete.

Structure and tautomerism of tenuazonic acid—A synergetic computational and spectroscopic

The neighbor-joining method: A new method for reconstructing phylogenetic trees.

Butremycin, the 3-Hydroxyl Derivative of Ikarugamycin and a Protonated Aromatic Tautomer of 5′-Methylthioinosine from a Ghanaian Micromonospora sp. K310

A new actinomycete strain Micromonospora sp. K310 was isolated from Ghanaian mangrove river sediment. Spectroscopy-guided fractionation led to the isolation of two new compounds from the fermentation culture. One of the compounds is butremycin (2) which is the (3-hydroxyl) derivative of the known Streptomyces metabolite ikarugamycin (1) and the other compound is a protonated aromatic tautomer of 5′-methylthioinosine (MTI) (3). Both new compounds were characterized by 1D, 2D NMR and MS data. Butremycin (2) displayed weak antibacterial activity against Gram-positive S. aureus ATCC 25923, the Gram-negative E. coli ATCC 25922 and a panel of clinical isolates of methicillin-resistant S. aureus (MRSA) strains while 3 did not show any antibacterial activity against these microbes

Houssen, Wael

CLoK

A new actinomycete strain Micromonospora sp. K310 was isolated from Ghanaian mangrove river sediment. Spectroscopy-guided fractionation led to the isolation of two new compounds from the fermentation culture. One of the compounds is butremycin (2) which is the (3-hydroxyl) derivative of the known Streptomyces metabolite ikarugamycin (1) and the other compound is a protonated aromatic tautomer of  5′-methylthioinosine (MTI) (3). Both new compounds were characterized by 1D, 2D NMR and MS data. Butremycin (2) displayed weak antibacterial activity against Gram-positive S. aureus ATCC 25923, the Gram-negative E. coli ATCC 25922 and a panel of clinical isolates of methicillin-resistant S. aureus (MRSA) strains while 3 did not show any antibacterial activity against these microbes

Multidisciplinary Digital Publishing Institute

Crossref

Butremycin, the 3-Hydroxyl Derivative of Ikarugamycin and a Protonated Aromatic Tautomer of 5′-Methylthioinosine from a Ghanaian Micromonospora sp. K310

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