A versatile platform for efficient cell lysis using a combination of acoustic and
electric fields in a microchannel is presented. Cell membrane disruption is triggered by
electric fields inducing electroporation and then lysis. The principle of optoelectronic
tweezers (OET) is applied to control the electric field strength and a surface acoustic wave
transducer is attached to an OET chip to implement acoustic tweezing (AT). The system is
characterized in terms of spatial control of electric fields, single cell precision and lysi
