Maternal Vitamin D deficiency may be a risk factor for transient tachypnea of the newborn [Maternal Vitamin D Eksikligi Yenidoganin Geçici Takipnesi Için Bir Risk Faktörü Olabilir]

Abstract

Objective: The aim of the study, to evaluate whether maternal vitamin D deficiency is a risk factor for transient tachypnea of the newborn (TTN). Material and Methods: In this study, 25-hydroxy vitamin D3 (25(OH)D3) levels of 34 newborn with TTN and their mothers and 68 healthy controls were compared. The factors that can effect VD deficiency were evaluated with a questionnaire. 25(OH)D3 levels was measured with isotope dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS). The correlation between 25(OH)D3 level of mothers and newborns were calculated. Results: Serum 25(OH)D3 levels were normal, at mothers 22 (32.5%) in the control group and 4 (11.7%) in TTN group, at neonates 10 (14.7%) and 2 (5.8%) respectively. Mean maternal 25 (OH) D3 levels 15.06±6.9 at control group and 11.6±5.4 TTN group (p=0.05). And cord blood 25 (OH) D3 levels 12.3±4.8 at control group and 7.4±3.8 TTN group (p<0.01). Strong and significant correlation was observed between the maternal blood and umblical cord 25(OH)D3 level (r=0.8, p<0.001). Body mass index, and seaside vacation time and season were found to be effective factors in the maternal vitamin D levels. Conclusion: Both maternal and neonatal VD deficiency may be a risk factor for TTN. Copyright © 2015 by Türkiye Klinikleri