Not AvailablePeste des petits ruminants (PPR) is a highly contagious disease of small
ruminants that leads to high morbidity and mortality thereby results in
devastating economic consequences to the livestock industry. PPR is currently
endemic across most parts of Asia and Africa, the two regions with the highest
concentration of poor people in the world. Sheep and goats in particularly
contribute significantly towards the upliftment of livelihood of the poor and
marginal farmers in these regions. In this context, PPR directly affecting the
viability of sheep and goat husbandry has emerged as a major hurdle in the
development of these regions. The control of PPR in these regions could
significantly contribute to poverty alleviation, therefore, the Office
International des Epizooties (OIE) and Food and Agricultural Organization (FAO)
have targeted the control and eradication of PPR by 2030 a priority. In order to
achieve this goal, a potent, safe and efficacious live-attenuated PPR vaccine
with long-lasting immunity is available for immunoprophylaxis. However, the
live-attenuated PPR vaccine is thermolabile and needs maintenance of an effective
cold chain to deliver into the field. In addition, the infected animals cannot be
differentiated from vaccinated animals. To overcome these limitations, some
recombinant vaccines have been developed. This review comprehensively describes
about the latest developments in PPR vaccines.Not Availabl
