Dugotrajno liječenje kisikom primjenjuje se kod bolesnika s kroničnom respiracijskom insuficijencijom.
Najčešći uzrok kronične respiracijske insuficijencije je kronična opstruktivna plućna bolest (KOPB), čiji je tijek unatoč terapiji progresivan i dovodi do respiratorne invalidnosti, te smanjenja kvalitete života. SF-36 je generički upitnik za procjenu kvalitete života vezanu za zdravlje (KŽVZ), kojim je moguće uspoređivati
kvalitetu života bolesnika s različitim bolestima. Cilj rada je bio upitnikom SF-36 usporediti KŽVZ dvije skupne bolesnika, koji koriste kroničnu nadomjesnu terapiju i to: bolesnika na dugotrajnom liječenju kisikom (DLO2) i bolesnika na kroničnoj hemodijalizi (KH). Kod bolesnika s KOPB na DLO2 ispitali smo povezanost pojedinih dimenzija SF-36 s parametrima plućne funkcije. U ispitivanje je uključen 51 bolesnik na DLO2 od kojih je njih 47 (92%) imalo dijagnozu KOPB. Kontrolna skupina su bila 52 bolesnika na KH.
Rezultati su pokazali da su obje skupine bile podjednake po raspodjeli spola i duljini trajanja kronične nadomjesne terapije. Bolesnici na DLO2 bili su statistički značajno stariji i imali su statistički značajno nižu samo dimenziju fizičkog funkcioniranja u odnosu na skupinu bolesnika na KH (p < 0,001). Kod bolesnika s
KOPB na DLO2, postbronhodilatatorni forsirani ekspiratorni volumen u prvoj sekundi i parcijalni tlak kisika arterijske krvi statistički su značajno pozitivno korelirali s dimenzijom fizičkog funkcioniranja (R + 0,469/p 0,002 i R + 0,301/p 0,039). Ograničena sposobnost fizičkog funkcioniranja u bolesnika koji provode DLO2 može se objasniti zaduhom, kao osnovnim simptomom plućnih bolesnika. Forsirani ekspiratorni volumen u prvoj sekundi i parcijalni tlak kisika arterijske krvi, parametri su koji odražavaju težinu plućne bolesti, pa je očekivana njihova korelacija s dimenzijom fizičkog funkcioniranja.Long-term oxygen therapy is used in patients with chronic respiratory failure. The most common cause of chronic respiratory failure is chronic obstructive pulmonary disease (COPD). The course of the disease is progressive despite therapy, and leads to espiratory disability and reduced quality of life. SF-36 is a generic
questionnaire for the evaluation of the quality of life, and the parameters measured are not specific to the disease, so it is possible to compare the quality of life in patients with various diseases. The aim of the study was to compare the health related quality of life (HRQL) measured by SF-36 for two groups of patients who
use chronic replacement therapy: patients on long-term oxygen therapy (LTOT) and patients on chronic haemodialysis (CH). In patients with COPD on LTOT, we examined the association between the dimensions of SF-36 with parameters of pulmonary function. The study included 51 patients on LTOT, 47 (92%) of them had COPD diagnosis. The control group was 52 patients on CH. The results showed that both groups were comparable for sex distribution and duration of chronic replacement therapy. Patients on LTOTwere significantly older and had a significantly lower dimension of physical functioning in comparison with those in CH (p<0.001). In patients with COPD on LTOT postbronchodilatatory forced expiratory volume in one second and arterial oxygen tension significantly positively correlated with the dimension of physical functioning (R +0.469/p 0.002 and R +0.301/p 0.039). Limited ability of physical functioning in patients on LTOT can be explained by dyspnea as the core symptom of pulmonary patients. Forced expiratory volume
in the first second and arterial oxygen tension reflect the severity of lung disease so their correlation with the dimension of physical functioning is expected
