Iminosugars represent the most promising class of therapeutically useful glycomimetics. Because of their ability to mimic structure and properties of natural monosaccharides, iminosugars are able to interfere with disease-related carbohydrate-processing enzymes. Despite their great therapeutic potential, iminosugars suffer of poor selectivity, thereby leading to the onset of undesired side effects after prolonged administration. In this area, a valid alternative is offered by L-iminosugars. The last ones are non-superimposable mirror images of natural iminosugars; studies have demonstrated that they act as either inhibitors or chaperones of various glycosidases, although working in a more markedly selective manne
