Prognosis after Aortic Valve Replacement with Mechanical Valves and Bioprostheses: Use of Meta-analysis and Microsimulation

Abstract

Aortic valve replacement (AVR) is a surgical procedure aimed at replacing a diseased aortic valve with a prosthetic device. The prognosis of a patient after AVR depends on many interrelated factors. The objective of this thesis was to further develop and utilize the microsimulation methodology to determine the prognosis of patients after AVR with mechanical valves and bioprostheses, which in turn could assist in the optimal choice of a valve prosthesis for a given patient