In this paper we present a novel Navigation and Guidance System (NGS) for Unmanned Aerial Vehicles (UAVs) based on Vision Based Navigation (VBN) and other avionics sensors. The main objective of our research is to design a lowcost and low-weight/volume NGS capable of providing the required level of performance in all flight phases of modern small- to medium-size UAVs, with a special focus on automated precision approach and landing, where VBN techniques can be fully exploited in a multisensory integrated architecture. Various existing techniques for VBN are compared and the Appearance-based Navigation (ABN) approach is selected for implementation
