Agapow, P.-M.

Baud, M.

Bigarré, L.

Gray, T.

Jonstrup, Søren Peter

Mikkelsen, Susie Sommer

Olesen, Niels Jørgen

Panzarin, V.

Agapow, P. M.

Online Research Database In Technology

Fishpathogens.eu/noda: A free and handy online platform for betanodavirus targeted research and datasharing

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Downloaded from orbit.dtu.dk on: Dec 20, 2017Fishpathogens.EU/NODA: A Free and Handy Online Platform for BetanodavirusTargeted Research and Data SharingPanzarin, V.; Mikkelsen, Susie Sommer; Jonstrup, Søren Peter; Bigarré, L.; Baud, M.; Gray, T.; Agapow,P.-M.; Olesen, Niels JørgenPublication date:2013Document VersionPublisher's PDF, also known as Version of recordLink back to DTU OrbitCitation (APA):Panzarin, V., Mikkelsen, S. S., Jonstrup, S. P., Bigarré, L., Baud, M., Gray, T., ... Olesen, N. J. (2013).Fishpathogens.EU/NODA: A Free and Handy Online Platform for Betanodavirus Targeted Research and DataSharing. Poster session presented at 16th International Conference on Diseases of Fish and Shellfish, Tampere,Finland.DATABASE PRESENTATION WHICH INFORMATION CAN BE UPLOADED? HOW CAN THE DATABASE BE ACCESSED? FISHPATHOGENS.EU/NODA: A FREE AND HANDY ONLINE PLATFORM FOR BETANODAVIRUS TARGETED RESEARCH AND DATA SHARING V Panzarin1*, SS Mikkelsen2*, SP Jonstrup2, L Bigarré3, M Baud3, T Gray4, P-M Agapow5, NJ Olesen2   * These authors equally contributed to this work  1 Research & Innovation Department - Division of Comparative Biomedical Sciences, OIE Reference Laboratory for Viral Encephalopathy and Retinopathy, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell’Università 10, 35020 Legnaro, PD, Italy 2 Section for Fish Diseases, Division of Poultry, Fish and Fur Animals, National Veterinary Institute, Technical University of Denmark, DK-8200 Århus N, Denmark 3 Fish Viral Pathologies Unit, Laboratoire de Ploufragan/Plouzané, ANSES, Technopole Brest-Iroise, 29200 Plouzané, France 4 Symantix Ltd, Wiltshire SN4 9BN, United Kingdom 5 Bioinformatics, Centre for Infections, Health Protection Agency (UK), 61 Colindale Avenue, London NW9 5EQ, United Kingdom Betanodaviruses are responsible for a severe neuropathological disease known as Viral Nervous Necrosis (VNN) that can affect a broad range of fish species worldwide. Betanodavirus genome consists of two single stranded positive sense RNA molecules, which are susceptible to reassortment events. The phylogenetic analysis of both genetic segments allowed the identification of at least four betanodavirus genotypes, namely RGNNV, SJNNV, BFNNV, TPNNV, as well as the two reassortants RGNNV/SJNNV and SJNNV/RGNNV. The infectivity of betanodavirus to an increasing number of fish species, its wide geographical extent and its economical and ecological impact, highlight the need of a platform for sharing epidemiological and molecular data.  Fishpathogens.eu is a website developed and maintained by the European Union Reference Laboratory for Fish Diseases (EURL-FISH). It has been previously launched for Viral Haemorrhagic Septicaemia (VHS) and Infectious Haematopoietic Necrosis (IHN), and have proven to be a valuable tool for experts targeted research. With the aim of collecting molecular and epidemiological information on betanodavirus, relevant for its control and research study, we extended FishPathogens.eu to also comprise VNN. The present database is going to be a useful tool to better understand betanodavirus diffusive dynamics and ecological features, as well as VNN epidemiology. Isolate information   Sampling date  Sample information  Geographical location  Water environment  Host species  Epidemiology information  Laboratory source  … Sequence information   Nucleotide sequence  Gene region(s)  Protein name(s)  Sequencing method  Basic annotation  Genotype/Genogroup …   HOW TO RETRIEVE INFORMATION? WHICH TOOLS ARE PROVIDED? Search possibilities by...  Gene region(s) Geographical location Keyword BLAST Sampling date …    Login is required to upload and download information  Everyone can register at www.fishpathogens.eu  Without registering it is still possible to browse reports  Everyone are encouraged to upload new reports      Output   .fasta sequences .csv (Excel)  .kml (Google maps) .Newick (phylogenetic tree) New function! Sequence comparison using .fasta files Tree building using neighbour-joining Round or square phylogenetic trees Export in Newick format    The development of Fishpathogens.eu was funded by the FP6-2004-Food-3-A project EPIZONE. Further maintenance and development is funded by the European Commision financial aid for running the European Reference Laboratory for Fish Diseases. 

Fishpathogens.EU/NODA: A Free and Handy Online Platform for Betanodavirus Targeted Research and Data Sharing

http://orbit.dtu.dk/ws/files/73351142/Fishpathogens.eu-noda.pdf

Fishpathogens.EU/NODA: A Free and Handy Online Platform for Betanodavirus Targeted Research and Data Sharing

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