Prostate-Specific Membrane Antigen PET/Magnetic Resonance Imaging for the Planning of Salvage Radiotherapy in Patients with Prostate Cancer with Biochemical Recurrence After Radical Prostatectomy

Abstract

Prostate-specific membrane antigen (PSMA) PET/magnetic resonance (MR) imaging can help distinguish between patients with prostate cancer with locoregional recurrence and those with distant metastases, even at low prostate-specific antigen levels. PSMA PET/MR imaging may have advantages compared with PET/computed tomography for the detection of local recurrence and anatomic correlates to PET-positive lymph node and bone lesions. PSMA PET/MR imaging can help in making informed treatment decisions in patients with biochemical recurrence after radical prostatectomy. PSMA PET/MR imaging enables dose-escalated and metastases-directed salvage radiotherapy in patients with biochemical recurrence after radical prostatectomy