The one-pot three component condensation of catechol and resorcinol with aromatic aldehydes and amides, thioamides such as urea, thiourea, thiosemicarbazide and acetamide under solvent free and neutral conditions to afford urea, thiourea and amide derivatives in high yields. The antitumor activity of some of the synthesized products was tested. Keywords: Three component condensation; 4H-benzo[e]-[1,3]oxazin-7-ol; Dioxoindenylurea; Antitumor activity
