research
Mycophenolate mofetil in kidney transplantation
- Publication date
- 23 May 2001
- Publisher
- Mycophenolate mofetil is a new immunosupressive drug, exhibiting its effect through
inhibition of proliferation ofT- and B-Iymphocytes. Superior efficacy of mycophenolate
mofetil compared to azathioprine, in combination with cyclosporine and prednisone, in the
prevention of acute rejection in organ transplantation has made mycophenolate mofetil one of
the standard immunosupressive drugs after transplantation. Mycophenolate mofetil also is an
interesting candidate drug for many other, mainly auto-immune mediated diseases. The use of
mycophenolate mofetil in several of these diseases is discussed. The defmitive place of
mycophenolate mofetil will depend on the results of randomised trials currently under way.