research
Central precocious puberty and gonadotropin releasing hormone agonist treatment
- Publication date
- 18 December 1996
- Publisher
- In order to understand the processes occurring during precocious puberty, one
needs to specify what is currently known about normal pubertal development.
Puberty can be defined as a maturational process of the hypothalamic-pituitarygonadal
axis, which results in the development of the gonads and,
concomitantly, in the physical and physiological processes which constitute
adulthood and the capacity to reproduce.
The regulation of puberty is a very complex process, involving the hormonal
interaction of the cells in the hypothalamus, pituitary and gonads. A central role
in this process is played by the Gonadotropin Releasing Hormone (GnRH or
LHRH: Luteinizing Hormone Releasing Hormone) which is produced and
secreted by the hypothalamus.