Risk Factors in Cause and Course of Multiple Sclerosis

Abstract

Multiple sclerosis (MS) is a leading non-traumatic cause of disability in young adults. It is a chronic neurological disorder characterized primarily by central nervous system (CNS) inflammation, myelin loss, and axonal pathology, resulting in progressive neurological dysfunction. Initially, inflammation is transient and partial remyelination occurs. MS is presumed to be an autoimmune disorder arising from complex interactions of both environmental and genetic factors