Genetic and Dietary Determinants of Homocysteine in Relation to Bone Health

Abstract

Osteoporosis is characterized by low bone mineral density (BMD), and deterioration of the bone microarchitecture leading to an increased risk of fracture 1. Osteoporotic fractures are a major health problem in the western society; they are associated with increased morbidity and mortality and with substantial economic costs. In the coming years, the number of fractures will increase throughout the world as the population ages, so prevention of fractures with inexpensive and well-established interventions is becoming increasingly important