thesis
Pro- and antioxidants and risk of atherosclerosis and coronary heart disease in the elderly
- Publication date
- 19 May 1999
- Publisher
- Coronary heart disease (CHD) is an increasing global problem carrying heavy social
and economic costs. Coronary heart disease is responsible for about 50% of
cardiovascular mortality, which itselfs accounts for 30-50% of all deaths in developed
nations t. It is the major cause of premature death, in women as in men - women
lagging behind men by some ten years in this age-related disease. Knowledge on risk
factors for CHD has accumulated in recent years. Research evidence now lends strong
support to the view that CHD is in part preventable by reduction of modifiable risk
factors. The greater the number of risk factors known to be causally related to the
disease, the greater the power to reduce the disease burden in the community by
reducing the levels of such pathogenic risk factors, though depending on the
modifiability of the risk factors and their strength related to disease. Diet is among the
modifiable risk factors and provides a simple and non-pharmacologic method for
prevention of atherosclerosis and coronary heart disease.