This article aims to empirically examine the concept of a destination region using a case study approach. Two conflicting hypotheses are considered for the spatial structure of tourism in Orlando\u27s destination region: the bubble pattern vis-à-vis a dispersed pattern. Locational concentration and the industrial mix of Orlando\u27s tourist-related firms are examined by analyzing data revealing their location and business specialization. Findings reveal the concentration of the accommodation and dining firms near the theme parks area in a bubble-like pattern. Conversely, smaller scale attractions, convention services, and visitor and professional services tend to locate in high proportions outside of the core area. Implications are discussed from both theoretical and practical perspectives