Andresen, Thomas Lars

Henriksen, Jonas Rosager

Johansen, Pia Thermann

S. Jensen, Simon

This invention concerns a liposome comprising lipids and at least one active ingredient, wherein at least one of the lipids is a cationic lipid; said liposome exhibiting a net positive charge at physiological conditions at which said liposome preferentially adheres to monocytes in freshly drawn blood when compared to adherence to granulocytes, T-lymphocytes, B- lymphocytes and/or NK cells in freshly drawn blood, to a lipid-based pharmaceutical composition comprising said liposomes and their use in monocytic associated prophylaxis, treatment or amelioration of a condition such as cancer, an infectious disease, an inflammatory disease, an autoimmune disease or allergy

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Cationic liposomal drug delivery system for specific targeting of human cd14+ monocytes in whole blood

http://orbit.dtu.dk/ws/files/84835550/WO2013135800A1.pdf

Cationic liposomal drug delivery system for specific targeting of human cd14+ monocytes in whole blood

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