Erratum to: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer, in: Clinical Epigenetics 2015 7:126 (https://doi.org/10.1186/s13148-015-0159-0

Beckmann, MW

Fasching, PA

Gao, Y

Jones, A

Ruebner, M

Teschendorff, AE

Widschwendter, M

UCL Discovery

Gao et al. Clinical Epigenetics  (2016) 8:63 DOI 10.1186/s13148-016-0231-4ERRATUM Open AccessErratum to: The integrative epigenomic-transcriptomic landscape of ER positivebreast cancerYang Gao1, Allison Jones2, Peter A. Fasching3, Matthias Ruebner3, Matthias W. Beckmann3,Martin Widschwendter2 and Andrew E. Teschendorff1,2,4*ErratumUnfortunately, after publication of the original version ofthis article [1], we noticed an error in Figure S8 inAdditional file 1. Specifically, the error relates to the legendof the figure, as what is being diplayed in this figure is notthe shortest path between pairs of top ranked features, butthe smallest number of path links one needs to remove inorder for the pair of features to be disconnected. Unfortu-nately, this completely alters the corresponding statementin the last paragraph of the Results section, since thesmaller average path link number for DNA methylation, asshown in Figure S8, means that in effect top ranked DNAmethylation alterations occur more distantly apart on thenetwork than top-ranked copy-number alterations. Thisdoes not however alter the conclusion about DNA methyla-tion exhibit coordinated changes across samples, as shownin Fig. 6, since the analysis presented in Figure S8 does notconsider alterations in individual samples, whereas the datashown in Fig. 6 does. Hence, the main conclusion thatDNA methylation alterations in FEM modules exhibit co-ordination modularity is unaffected. However, top-rankedDNA methylation alterations map further apart on thenetwork than corresponding copy-number alterations.* Correspondence: a.teschendorff@ucl.ac.uk; andrew@picb.ac.cn1CAS Key Lab for Computational Biology, CAS-MPG Partner Institute forComputational Biology, Chinese Academy of Sciences, Shanghai Institute forBiological Sciences, 320 Yue Yang Road, Shanghai 200031, China2Department of Women’s Cancer, University College London, 74 HuntleyStreet, London WC1E 6BT, UK© 2016 The Author(s). Open Access This articInternational License (http://creativecommonsreproduction in any medium, provided you gthe Creative Commons license, and indicate if(http://creativecommons.org/publicdomain/zeAuthor details1CAS Key Lab for Computational Biology, CAS-MPG Partner Institute forComputational Biology, Chinese Academy of Sciences, Shanghai Institute forBiological Sciences, 320 Yue Yang Road, Shanghai 200031, China.2Department of Women’s Cancer, University College London, 74 HuntleyStreet, London WC1E 6BT, UK. 3Department of Gynaecology and Obstetrics,Friedrich-Alexander University Erlangen-Nuremberg, University ClinicErlangen, Erlangen, 91054, Germany. 4Statistical Genomics Group, PaulO’Gorman Building, UCL Cancer Institute, University College London, 72Huntley Street, London WC1E 6BT, UK.Received: 25 May 2016 Accepted: 25 May 2016References1. Gao Y, Jones A, Fasching PA, Ruebner M, Beckmann MW, Widschwendter M,et al. The integrative epigenomic-transcriptomic landscape of ER positivebreast cancer. Clin Epigenetics. 2015;7:126. doi:10.1186/s13148-015-0159-0.•  We accept pre-submission inquiries •  Our selector tool helps you to find the most relevant journal•  We provide round the clock customer support •  Convenient online submission•  Thorough peer review•  Inclusion in PubMed and all major indexing services •  Maximum visibility for your researchSubmit your manuscript atwww.biomedcentral.com/submitSubmit your next manuscript to BioMed Central and we will help you at every step:le is distributed under the terms of the Creative Commons Attribution 4.0.org/licenses/by/4.0/), which permits unrestricted use, distribution, andive appropriate credit to the original author(s) and the source, provide a link tochanges were made. The Creative Commons Public Domain Dedication waiverro/1.0/) applies to the data made available in this article, unless otherwise stated.

The integrative epigenomic-transcriptomic landscape of ER positive breast cancer (vol 7, 126, 2015)

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The integrative epigenomic-transcriptomic landscape of ER positive breast cancer (vol 7, 126, 2015)

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