Many beehive products such as propolis, Manuka honey, bee pollen, and royal jelly have been used by people due to their popular known health benefits. A novel bee product, bee venom, has demonstrated effective in treating various debilitating conditions, and thus bee venom therapy has been the subject of scientific studies to quantify its medical efficacy. Although bee venom has been used for millennia in Eastern medicine, modern bee venom therapy (BVT) originated in Europe in the 19th century, but was brought to the U.S. by Dr. Bodog Beck after World War I. The treatment became more widespread in the West as the 20th century progressed (Cooney et al, 2011). There are currently various application methods with the most popular being apipuncture (acupuncture with bee venom where needles are initially dipped into the venom before applied to the patient) and bee venom injections (Mohammadi et al, 2015). The multiple beneficial effects of bee venom include increased blood circulation, stimulation of the pituitary-cortical system, and reduced pain and inflammation (Mohammadi et al, 2015). These responses help treat the symptoms of many diseases and chronic inflammatory conditions. With additional research, the use of bee venom can be included as a means to safely alleviate the symptoms of several autoimmune diseases, especially rheumatoid arthritis (RA)
