KARUNCHEMBAI ILAI CHOORANAM:
The herb Karunchembai Ilai was collected from Erode Dist., and purified then powered and stored and was subjected to various studies.
• Karunchembai leaves were selected for this study to evaluate the Anti histamine activity, and to prove its efficacy and safety in Eczema.
• The Gunapadam aspect expressed that the drug possess good effect on Eczema and other skin diseases.
• Pharmacological study showed significant anti-histaminic activity, anti-microbial activity, anti-inflammatory activity.
• The microbial studies of the test drug proves highly sensitivity to all micro organism.
• Scanning Electron microscope (SEM) the trial drug have good nano particle size that indicated absorption is very good and pharmaco therapeutic value is good.
• Qualitative analysis for the trial drug evaluated the presence of Triterpenoid, Flavonoid, Saponins, Glycosides, Tannin and Phenol.
• The clinical study showed improvement in symptoms like itching, oozing, erythema, scaling, pustules etc.
CONCLUSION:
The medicinal plant Karunchembai Ilai Chooranam was taken for the study mainly to evaluate anti-histamine activity in the treatment of Eczema.
• The drug is easily available and preparation is very simple as per evidences about the plant, thus proving the efficacy of the drug in the treatment of Eczema.
• Qualitative analysis proved the presence of Triterpenoid, Flavonoid, Tannin, Saponin and Phenols.
• Presence of Iron increases the Hb production and helps in transport of O2 to the tissues also participates in cellular oxidation mechanisms.
• The trial medicine is less expensive.
• No any adverse effects has been reported.
Hence Karunchembai Ilai Chooranam proves itself as a satisfactorily effective drug for Eczema.
ASHTA GUNMA THIRAAVAGAM:
Ashta Gunma Thiraavagam was selected for this study to establish the safety and efficacy of its diuretic activity
• The Physico – chemical analysis shows the precence of Potassium, Iron, Calcium, Sulphate and Chloride.. These elements are useful in eliminating urine from the body and helps in many metabolic functions of our body.
• Acute and Sub acute toxicological studies shows strong evidence of the drug. The results showed.
• The pharmacological analysis showed that the drug has got significant efficacy.
• In clinical study, the drug has showed improvement in 65% of cases.
• The patients were responding well from the beginning of the treatment and no adverse effects were reported.
CONCLUSION:
The evaluation of the efficacy of Ashta Gunma Thiraavagam for diuretic activity in the managements of oedema, urolithiasis and hypertension gave significant results.
• The presence of chloride, calcium and sulphate enhances the diuretic activity.
• Pharmacological animal study shows that Ashta Gunma Thiraavagam acts as potent diuretic comparable to that of standard drug.
• The drug gives very good therapeutic effect because of its easy absorption.
• Clinically, the drug relieved the symptoms of SHT,Urolithiasis,oedema and showed net increase in 24 hrs urine output.
• No adverse reactions were produced during the period of the clinical study.
So I conclude that Ashta Gunma Thiraavagam act as a good diuretic
