The biography of Daniel Ernst Jablonski (1660-1741), bishop of the Moravian Brethren in Poland and at the same time a most influential Prussian court preacher, reflects the relationships between East-, Central- and Western Europe during the Early Enlightenment. Both, his Grandfather, Jan Amos Comenius, and his father, were bishops of a church, which had been exiled from Czechia to Poland, where Daniel Ernst Jablonski was born. He studied in Frankfurt (Oder), and at the Christ Church College in Oxford, where he became friend with several prominent members of the Anglican Church. He was an outstanding member in the European respublica literaria in different fields, Orientalistic, i.e. Jewish and biblical studies, and he was highly esteemed as a scholar in Old Slav church history. These were good preconditions for making him a bridge builder between nations and ideas. Side by side with Gottfried Wilhelm Leibniz (1646-1716) he worked at the foundation of the later-on famous Prussian Academy of Sciences and over decades he worked at the union of the separated Protestant churches. For his lifelong commitment to the religious tolerance and to the rights of religious minorities, along with his scientific work, he deserves to be considered a representative (if in a moderate way) of the European Enlightenment