Roentgenoscopy was used as a method to determine the quality of hybrid seeds and to predict the development of viable plants from interspecific hybridization. The seeds were grouped into five classes of quality (embryo classes) depending on embryo size and degree of endosperm development As the index number of a class increased, the proportion of plantlets and vigorous plants produced also increased. In order to evaluate genotypic peculiarities of the original forms and seedlings, the seedlings were studied at the juvenile stage of ontogeny. Analysis of development of the hybrids studied during 5-6 years under conditions of complex infection pressure at a special planting site made it possible to evaluate the degree of their resistance to phylloxera, pathogenic soil microflora and fungal diseases and to eliminate susceptible genotypes. The heritability of resistance to fungal diseases (mildew, oidium, grey rot) and phylloxera was studied, conclusions were made concerning the combining ability of the original forms, and these forms were evaluated as donors of the desirable characters. Using transgressive resistant hybrids as donors in backcrossing provided improved quality with a broad range of resistance variability, which made it possible to select promising genotypes