The test drug Siddhar Kuligai was selected from the siddha literature “Veerama Munivar Vagada Thirattu-part1" its Standardization and Pharmacological screening (anti inflammatory, analgesic activity) in an animal model and anticancer activity in in-vitro cell line model. The dissertation started with an introduction explaining about the siddha concept and role of the test drug in treating cancer.
• The test drug was prepared properly by the given procedure. All the ingredients were identified and authenticated by the respective field experts.
• Review of literature in various categories was carried out. Siddha aspect, botanical aspect and pharmaceutical review disclosed about the drug and the disease. Pharmacological review was done to establish the methodologies.
• The drug was subjected to analysis such as, physicochemical, chemical analysis, phytochemical, Instrumental and pharmacological analysis which provided the key ingredients present in the drug thus it accounts the efficacy of the drug.
• Identification of functional groups was engaged by using Fourier Transform Infra Red spectroscopy [FTIR].
• The partical size and identification and quantitative analysis of chemical elements of siddhar kuligai were assessed by SEM with EDAX and XRF.
• The Siddhar Kuligai does not show the evidence for the presence of any of the aflatoxins.
• The Instrumental analysis report reveals that the heavy metals like Lead, Cadmium Arsenic and Mercury are within the permissible limits.
• Pharmacological study was done. It revealed the Anti-infalmmatory, Analgesic activities of trail medicine in animal model viz., Wistar albino rats and swiss albino mice and anti-cancer activity in in-vitro cell line model This study suggests Siddhar Kuligai has remarkable medicinal value in the treatment of cancer.
• Results and discussion gives the necessary justifications to prove the potency of the drug
