BACKGROUND & OBJECTIVES:
A prospective study was carried out to find the variations in lipid profile in smokers when compared to non-smokers. To study the alterations in lipid profile in terms of severity of smoking.
MATERIALS AND METHODS:
This study was carried out among 200 patients who attended Government Rajaji Hospital, Madurai for various ailments. The population was divided into 100 non-smokers and 100 smokers. The smokers were further divided into three groups depending on the intensity of smoking. Serum lipid profile was analyzed in all subjects.
RESULTS:
Lipid Profile -
TC : Non-Smokers (Mean ± Std) 161.18±26.77, Smokers (Mean ± Std) 191.96±31.37, P-Value < 0.001.
Lipid Profile -
TG : Non-Smokers (Mean ± Std) 103.58±26.26, Smokers (Mean ± Std) 164.29±28.95 P-Value < 0.001.
Lipid Profile - HDL : Non-Smokers (Mean ± Std) 49.58±8.57, Smokers (Mean ± Std) 44.72±9.96, P-Value = 0.002.
Lipid Profile -
LDL : Non-Smokers (Mean ± Std) 82.34±16.57, Smokers (Mean ± Std 103.08±18.66 < 0.001.
Lipid Profile -
VLDL :
Non-Smokers (Mean ± Std) - 21.69±6.42, Smokers (Mean ± Std) - 29.02±8.98 P-Value < 0.001.
Dyslipidemia was directly proportional to intensity of smoking.
INTERPRETATION AND CONCLUSION:
Increase in total Cholesterol, Triglycerides, LDL & VLDL were found in smokers of all age groups. Whereas HDL values showed inverse relationship. These changes were directly proportional to the severity of smoking. So, Tobacco smoking is associated with dyslipidemia which is atherogenic in nature
