In our prevalence study, 100 patients admitted as inpatients at Government General
Hospital are taken for our study to assess the hematological profile and the hemostatic profile.
All the patients were evaluated for the diagnosis of cirrhosis. Then patients were subjected to
investigations for the hematological profile and hemostatic profile. Patients were done liver
biopsy, upper GI endoscopy, USG abdomen and clinical signs for the diagnosis of cirrhosis.
Blood investigations were done to assess the anaemia, nature of anemia, WBCs total count and
differential count, platelet count, prothrombin time and APTT.
All the investigations were collected and tabulated. According to the study, the most
common anemia in cirrhotics is normochromic normocytic anaemia. Microcytosis occur in
patients with bleeding tendencies and macrocytosis occur mostly in alcoholics.
Leucopenia occurs in a small fraction of patients and leucocytosis occurs in patients
with history of repeated paracentesis and peritonitis. Eosinophilia is associated with parasitic
infections.
Thrombocytopenia is present in most of the cirrhosis patients and are associated with
increased bleeding tendencies. Most of the patients had increased prothrombin time and APTT
due to decreased synthesis of clotting factors.
Thus in cirrhosis patients most of them had abnormalities in haematological parameters
and hemostasis
