Dyslipidemia is a fairly common occurrence in CRF patients.
Cardiovascular mortality in patients with CRF is related to dyslipidemia.
This study was done to identify the lipid abnormalities and its
significance in CRF patients by comparing with age, sex and BMI of
matched healthy control population.
After institutional ethical clearance with an informed consent and
with inclusion and exclusion criteria, 56 cases of CRF were taken as
study cases and Three fasting lipid profile were estimated. 25 age, sex
and BMI matched healthy Population were taken as controls. The data
were entered in master sheet and analyzed statistically.
Dyslipidemia is seen in CRF patients. The total cholesterol, even
though it was high in CRF cases compared with controls, but the change
was not significant statistically. Triglycerides showed a statistically
significant increase in CRF cases. LDL-C was elevated in CRF cases but
the change was not significant statistically. HDL-C on the other hand
showed a statistically significant drop compared to controls. These lipid
abnormalities may be an important contributing factor to the
cardiovascular mortality in patients with CRF