A case control study was conducted on prevalence of
MAC in chronic kidney disease patients compared to subjects with
normal kidney function. After obtaining ethical committee clearance,
102 CKD patients and 100 non CKD subjects comparable in age
and sex distribution were selected randomly. After recording clinical
data, blood investigations and ultrasonographic study,
echocardiogram was done in all to look for MAC
Results on analysis showed significantly high MAC in CKD
patients. Among 102 CKD patients 10 (9.8%) had MAC while only
one(1%) had MAC in non CKD group. Among 10 who had MAC in
CKD group, 6 (60%) were in 40 to 60 age group and 4 (40%) were in
above 60 age group. In non CKD group MAC was present only in an
elderly female. In CKD patients MAC occurs even in younger age
group. Significant association of high levels of calcium, phosphorus
and calcium x phosphorus product with MAC was also noticed in the
study. Increased MAC in CKD patients may be due to altered calcium
and phosphorus metabolism in them. CAD was significantly high in
those with MAC which may be due to the burden of shared risk
factors for atherosclerosis in both groups
