Evaluation of Antimicrobial and Antitubercular Activity of 5-Nitro 2-Thiophene Carboxaldehyde by Invitro Method.

Abstract

AIM AND OBJECTIVES: The present study to evaluate the antibacterial activity of 5-Nitro 2-thiophene carboxaldehyde compound by Agar dilution and Agar diffusion method. To evaluate the antifungal activity of 5-Nitro 2-thiophene carboxaldehyde compound by Agar dilution method. To evaluate the anti-tubercular activity of 5-Nitro 2-thiophene carboxaldehyde compound by Microplate Alamar Blue Assay method (MABA) using H37Rv tubercular cell lines.Multiple drug resistance has developed due to the indiscriminate use of commercial antimicrobial drugs commonly used in the treatment of infectious diseases. In addition to this problem, antibiotics are sometimes associated with adverse effect on the host including hypersensitivity, immune supervision and allergic reaction. This situation forced scientist to search for new antimicrobial substances to search for new antimicrobial substances. Given the alarming incidence of antibiotic resistances in bacteria of medical importance, there is a constant need for new and effective therapeutic agents

    Similar works