A study on vitamin-D level and glycemic status in acute ischemic stroke and their impact.

Abstract

Stroke remains to be one of the leading causes of the mortality worldwide. The majority of the stroke as a result of occlusion of the blood supply to the brain leading to cerebral infarction (Ischemic stroke). The Vitamin D deficiency is present worldwide, and recent studies found that there is direct correlation between Vitamin D deficiency and ischemic stroke. The hyperglycemia on admission is associated with poor outcome in the patient with ischemic stroke. The hyperglycemia is associated poor salvage of the ischemic penumbra. The hyperglycemic ischemic stroke patient are associated with higher infarct volume on admission, a greater progression of the ischemic stroke, resulting in higher final infarct volume when compared with the patient who are euglycemia on admission. In this study, ischemic stroke patients fitting into the criteria are selected, and the Vitamin D are assessed, the glycemic status on admission is correlated with the infarct volume on admission and on 3rd to 7th day of the stroke by using MRI-Diffusion weighted images of the brain. Conclusion: In our study the results are Vitamin D deficiency common in ischemic stroke, and the hyperglycemia on admission is associated with higher infarct volume on admission, a greater progression of the ischemic stroke, resulting in higher final infarct volume when compared with the patient who are euglycemia on admission

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