Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
Waist circumference is a good predictor of the risk of heart diseases, but dana on the relationship between waist circumference and pulmonary diseases are sparse. The aim of this study was to investigate its influence on pulmonary function regarding exercise capacity in moderate and severe chronic obstructive pulmonary disease (COPD), according to Global Initiative for Lung Diseases (GOLD) stages. During 2009, a total of 70 COPD patients aged 33 to 80 years were stratified into GOLD 2 and GOLD 3 stages. Diagnostic separation between COPD severity groups was made upon percentage of predicted forced expiratory volume in 1 second. Anthropometric measures, lung function testing and prognostic scoring systems were assessed. Logistic regression analysis was used to make comparisons while taking into account the possible confounding factors. Waist circumference did not show substantial variations between GOLD 2 and GOLD 3 stages (p>0.5). There was a weak positive correlation between waist circumference and percent of predicted 6-minute walking distance (r=0.237; p=0.001). Another parameter, suprailiac skinfold, was significantly different between GOLD 2 and GOLD 3 stages (19.41 vs. 15.32 mm; p=0.047). Although waist circumference is a meaningful marker of abdominal obesity, which influences pulmonary function, we failed to prove its importance in correlation with functional lung capacity in a selected COPD population. However, suprailiac skinfold deserves greater attention and further evaluation.Povećani je opseg struka dobar predskazatelj rizika za razvoj srčanih bolesti, no gotovo da nema podataka o odnosu opsega struka i plućnih bolesti. Cilj ove studije bio je ispitati utjecaj veličine opsega struka na funkcionalnu plućnu sposobnost prema klasifikaciji GOLD (Global Initiative for Lung Diseases). Tijekom 2009. godine 70 bolesnika u dobi od 33 do 80 godina podijeljeno je u skupine GOLD2 i GOLD3 ovisno o težini bolesti. Dijagnostička razdioba ovih skupina temelji se na razlici dobivenih vrijednosti predviđenog forsiranog ekspiracijskog volumena u prvoj sekundi. Analizirane su brojne antropometrijske mjere, testovi plućne funkcije i prognostički bodovni sustavi. U statističkoj je obradi korištena logistička regresijska analiza. Razlika u veličini opsega struka između stupnjeva GOLD2 i GOLD3 nije dosegla statističku značajnost (p>0,5). Nađena je slaba pozitivna korelacija između opsega struka i postotka predviđene udaljenosti u 6-minutnom hodu (r=0,237; p=0,001). No, statistički značajna razlika između dviju ispitivanih skupina nađena je u debljini suprailijačnog nabora (19,41 prema 15,32 mm; p=0,047). Opseg struka je jedan od parametara koji definiraju abdominalnu pretilost. Iako pretilost utječe na plućnu funkciju, ova studija nije dokazala da postoji korelacija između veličine opsega struka i funkcionalne plućne sposobnosti u odabranoj populaciji bolesnika s kroničnom plućnom bolešću. No, daljnju evaluaciju i vrednovanje u kliničkoj praksi zaslužuje mjerenje suprailijačnog nabora
