Introduction: The central serotonergic (5-HT) system is closely involved in regulating various mental functions such as mood, anxiety, and impulsiveness. In this system, the serotonin transporters (5-HTT) and 5-HT1A receptors are particularly important as the key targets of pharmacotherapy for depression and anxiety disorders. However, there have been only a few reports regarding the intraindividual relationship between pre- and postsynaptic serotonergic functions. In the present study, we examined intraindividual relationship between 5-HTT and 5-HT1A receptors using PET.Neuroreceptor Mapping 2008 Pittsburgh, P
