Lithum salts have been widely used in the treatment of mood disorders, but the mechanism of action is still not clear. In this work, a methodology for two-dimensional Lithium-7 imaging on clinical systems is presented. The data were acquired using a phosphorus volume head coil that was re-tuned for the Lithium-7 frequency. A spectroscopic sequence was used to acquire the free induction decay (FID) after volume excitaion using a hard pulse. The results obtained on the head of patients undergoing lithium treatment(n=7, 0.6mEq/1 average serum level) demonstrate that images of adequate signal to noise ratio (100:1) can be obtained in acceptable imaging times(55 min) using the proposed methodology. The distribution of 7Li appears uniform in the brains of the patients studied
