Intoxications with drugs, household products and plants include approximately 70% of all cases reported to the STIZ. Among drugs the most frequent severe intoxications occur with benzodiazepines and antidepressives; therefore, the toxicological risk of these substances are investigated in more detail. In children, accidental intoxications with household products are most frequent. In these cases special emphasis must be put on preventive measures. Plants only rarely lead to severe intoxications; however, if toxic symptoms do occur, the analysis of their causality and overall risk for the patient can be a difficult task and frequently requires the involvement of a plant specialist