Brachi, Giulia

Ciardelli, Gianluca

Ferrari, Mauro

Mattu, Clara

Menichetti, Luca

Nizzero, Sara

English

Brachi Giulia

Mattu Clara

Menichetti Luca

Nizzero Sara

Ferrari Mauro

Ciardelli Gianluca

PORTO@iris (Publications Open Repository TOrino - Politecnico di Torino)

04 August 2020POLITECNICO DI TORINORepository ISTITUZIONALECore-Shell Nanoparticles for Cancer Imaging and Treatment / Brachi, Giulia; Mattu, Clara; Menichetti, Luca; Nizzero,Sara; Ferrari, Mauro; Ciardelli, Gianluca. - ELETTRONICO. - (2018). ((Intervento presentato al convegno Advances inTissue Engineering 2018 tenutosi a Houston (TX, USA) nel August 8-11, 2018.OriginalCore-Shell Nanoparticles for Cancer Imaging and TreatmentPublisher:PublishedDOI:Terms of use:openAccessPublisher copyright(Article begins on next page)This article is made available under terms and conditions as specified in the  corresponding bibliographic description inthe repositoryAvailability:This version is available at: 11583/2761006 since: 2019-10-17T13:02:02ZAdvances in Tissue EngineeringYour name, email and phone number    Giulia Brachi giulia.brachi@polito.it + 39 3292286993  Title and author(s)  Core-Shell Nanoparticles for Cancer Imaging and Treatment  Giulia Brachi a,c, Clara Mattu a,c, Luca Menichetti b, Sara Nizzero c, Mauro Ferrari c and Gianluca Ciardelli a,b  aPolitecnico di Torino, Torino, Italy bConsiglio Nazionale delle Ricerche, Pisa, Italy cDepartment of Nanomedicine, HMRI, Houston, TX    Abstract   In this work, polymer nanoparticles composed of a polyurethane (PUR) core and a cell-friendly lipid shell were designed (figure 1).                                     PUR chemistry was exploited to modulate the polymeric core affinity for drugs/probes of varying water solubility. The outer lipid shell was labeled with a photo-acoustic probe to combine complementary imaging techniques. We investigated whether the core/shell structure could be used for rationale design of particles with modulated core-dependent properties to accommodate different payloads, without affecting the surface-related properties, such as biodistribution, cell uptake and tumor accumulation.  

Core-Shell Nanoparticles for Cancer Imaging and Treatment

https://iris.polito.it/retrieve/handle/11583/2761006/280681/Advances%20in%20tissue%20Engineering%202018_Giulia%20Brachi.pdf

Core-Shell Nanoparticles for Cancer Imaging and Treatment

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