Helicobacter pylori, a gram negative microorganism, concomitant with a ramification of gastro-intestinal illnesses blanketed duodenal, non-ulcer dyspepsia, and gastric ulcer and active persistent gastritis. The frequency of H. pylori contamination ought to more than ninety % in patients showing sign and symptoms of gastrointestinal infections. It has been reported of affiliation of H. pylori infection with complication of stomach cancer. It may be transmitted through oro-fecal rely via the eating of waste-polluted water or meals. Combination of antibiotics and bismuth compounds found to be powerful in treating lively infection. Diagnosis of infection is through invasive testing techniques i.e. histology, Culture, based totally on endoscopy and biopsy, or non-invasive trying out strategies, which include serologic antibody assay, urea breath test and stool antigen test. Serologic antibody assay and UBT do no longer distinguish between a current infection and past cured infection. The stool antigen test is used to detect antigen presence inside the faeces that suggests lively infection. It can be extensively utilized to monitor the prognosis of disease and the recurrence. Prevention is by means of hygiene measures like hand washing practice and transmission control. If infection left untreated may also lead to critical hassle. Keywords: H. Pylori, Helicobacter Pylori, Clinical Revie
