Studies were conducted with model systems of influence of Drossinakis with electromagnetic (e.m.) fields and infrared thermal field (ITF) (Ignatov, Mosin, Niggli, Drossinakis, 2013). The purpose of research is to analyze effects over DNA. In the report is carried out analysis of effects over water and physiological saline. Results are achieved with blood serum of hamsters and physiological processes in hamsters with tumors. The analyses with water are conducted using the methods Nonequilibrium Energy Spectrum (NES) and Differential Nonequilibrium Energy Spectrum (DNES) (Antonov, 1992; Ignatov, 1998). Experiments are carried out with the influence of tumor cells of a mouse in water. It is observed reduction of DNES spectrum according to the control sample of cells in healthy animals. (Antonov, 1992). Reduction is also observed in DNES spectrum in blood serum of people having oncological diseases, compared to the one of healthy people (Ignatov, 2012). Such a reduction is most prevalent in (-0.1387 eV; 8.95 µm; 1117 cm-1). In research of the effects of e.m. fields in water and blood serum from hamsters the range is (-0.08 – -0.14 eV) (8.9 –15.5µm) (645–1129 cm-1). Research is conducted for the effects over Graffi tumor that was implanted in hamsters (Toshkova, Ignatov, Zvetkova, Ignatov, Gluhchev, Drossinakis, 2019). Studies are conducted with pH and oxidation redox potential (ORP) effects of e.m. fields over physiological saline (Gluhchev, Ignatov, Drossinakis, 2019). Keywords: Infrared thermal field (ITF), electromagnetic fields (e.m. fields), experimental Graffi solid tumor, energy spectrum, NES and DNES methods. DOI: 10.7176/JMPB/56-03 Publication date:May 31st 201