Malaria remains a global health challenge especially in sub-Sahara Africa where the most dangerous species thrive. It is a popular belief that the best way of halting the spread of any communicable disease is to adopt health preventive practices. A cross-sectional survey was carried out to determined malaria preventive practices among pregnant women in Ebonyi State, Nigeria. Stratified sampling technique was used in selecting 504 pregnant women attending antenatal clinic in 12 hospitals in the state. A face validated, self constructed questionnaire which was subjected to a reliability test using Cronbach Alpha method yielded a reliability value of 0.91. Data were analysed using descriptive statistics of mean and inferential statistics of T-test and ANOVA. Results showed that pregnant women often ( = 1.70-3.05) adopted most of the malaria preventive practices. There was a significant difference in 9 out of 11 malaria preventive practices adpted by women who reside in urban and rural areas in favour of women who reside in the urban areas. Level of education significantly affected malaria preventive practices in favour of women with post secondary education. Intervention efforts should focus on rural pregnant women and formulated to accommodate the less educated members of this group. Keywords: Malaria, Preventive practices, Pregnant women, Ebonyi State, Nigeri