The inhibition effect of famotidine drug towards the corrosion of C-steel in 0.5M H2SO4 was studied using weight loss, gasometry, potentiodynamic polarization and electrochemical frequency modulation (EFM) techniques, as well as, surface examination by SEM. The inhibition mechanism of FA is based on the adsorption process forming a film barrier layer protect the steel from acid attack. The adsorption is found to obey Frundlich model. The inhibition efficiency increased by increasing inhibitor concentration and decreased with temperature. Some thermodynamic parameters for adsorption process are deduced and discussed. Keywords: C-steel, famotidine, Adsorption, Corrosion