Condensation products obtained from the treatment
of uracil amidine with preformed or in situ generated
suitably substituted olefins unexpectedly undergo intramolecular
cyclisation during silica gel chromatography to generate
pyrido[2,3-d]pyrimidines. Various reaction conditions
arestudiedandthealterednatureoftheuracilamidinemoleculeisfurtherexploredbyreactingitwithdifferentsuitably
substituted alkene
