The International Institute for Science, Technology and Education (IISTE)
Abstract
Vitis vinifera L. is kind of grape grown widely in Asia, Europe and America.It has many nutritional and pharmacological uses in the Indian traditional medicine, also by European folk healers and many other nations, for treatment of many medical conditions such as nausea , thirst , cough , constipation , smallpox , cholera, hemorrhoids and some of skin and eye diseases.In the present study, Vitis vinifera L. leaves was collected from shrub, grown in IRAQ. The aqueous leaves extract used, was prepared and evaluated for kidney functions (urea, creatinine ,uric acid) and liver enzymes activity (AST,ALT) in induced hyperthyroidism female rabbits. Results showed significant decrease ( p<0.05) in levels and activities of the studied parameters .Our conclusion this herb may inhibits enzymes activity, that was activated by Levothyroxine sodium. So we think there is a relation between the drug and enzymes releasing sources. Keywords: Vistis vinifera L., L- thyroxin, Urea, Creatinine, Uric acid, AST, ALT