The International Institute for Science, Technology and Education (IISTE)
Abstract
The presence of Extended Spectrum Beta Lactamase (ESBL) producing organisms in abattoirs, a non-hospital community was investigated. A total of ten (10) isolates of Pseudomonas species out of twenty-six bacteria isolates expressing ESBL was obtained. The anti-pseudomonal activities of various solvent fractions of Milletia aboensis against the ESBL positive isolates of Pseudomonas species showed varying sensitivity. These results have suggested that Milletia aboensis possess potent anti-pseudomonal agents that could be used to treat infections due to Pseudomonas species expressing ESBL. These anti-pseudomonal metabolites are located in the ethanol, chloroform and methanol fractions but are absent in the ethyl acetate fractions. Keywords: Extended Spectrum Beta Lactamase, Milletia aboensis, Pseudomonas specie
