The International Institute for Science, Technology and Education (IISTE)
Abstract
The concept of drug targeting or site specific drug delivery was introduced first time by Paul Elrich in 1909, when he reported magic bullet to deliver a drug to the desired site of action without affecting the non target organs or tissues (Juliano, 1980) by associating the drug with a pharmacologically inactive carrier capable of conveying the drug selectively towards its target cells. The main goal of a site specific drug delivery system is not only to increase the selectivity and drug therapeutic index, but also to reduce the toxicity of the drug
