We present results concerning the non-perturbative evaluation of the
ghost-gluon running QCD coupling constant from Nf=2 twisted-mass lattice
calculations. A novel method for calibrating the lattice spacing, independent
of the string tension and hadron spectrum is presented with results in
agreement with previous estimates. The value of ΛMS is
computed from the running of the QCD coupling only after extrapolating to zero
dynamical quark mass and after removing a non-perturbative OPE contribution
that is assumed to be dominated by the dimension-two \VEV{A^2} gluon
condensate. The effect due to the dynamical quark mass in the determination of
\Lams is discussed.Comment: 33 pages, 6 fig