Raynaud’s syndrome is a cutaneous vasculitis associated with a variety of underlying conditions such as connective tissue disorders, occupational exposures, drugs and very rarely vaccines. We report a case of Hepatitis B vaccination-induced Raynaud’s vasculitis in a previously healthy 46-year-old male. The sequence of events along with acute onset of symptoms with confirmation of small vessel vasculitis by CT angiogram and exclusion of other recognized etiologies was consistent with vaccine-induced vasculitis. Although extremely rare, physicians must be made aware of instances of vaccination-induced vasculitis (small and medium vessel) in a patient presenting with vasculitic symptoms
